The GLP-1 Lab · by GLP-1 SOS
Dose increase
-
How to restart a GLP-1 after a break
Ask your prescriber first. After 2 or more missed weekly Wegovy doses, the label says to restart the dose build-up at a lower dose to spare your gut.
-
Brain fog on a GLP-1: causes and fixes
Brain fog is not a listed GLP-1 side effect and no trial has measured it. Low food, fluids and sleep are the usual suspects, and most of them are fixable.
-
Cold sweats and night sweats on a GLP-1
Sweating is not a listed GLP-1 side effect. Rule out low blood sugar first, mainly with insulin or a sulfonylurea; menopause and fever are common too.
-
How to dose compounded GLP-1s: units, mg and the syringe
Your dose is in mg; the syringe measures volume. On a U-100 syringe 100 units = 1 mL, and how many mg that holds depends on your vial’s mg/mL.
-
GLP-1 shortage: what to do when the pharmacy is out
The national semaglutide and tirzepatide shortages ended in 2024 and 2025. A local stock-out is usually brief: call other pharmacies, then your prescriber.
-
How long does GLP-1 fatigue last?
Usually days to a few weeks: the first month, the first weeks of each dose step, a day or two after each shot. Weeks on a steady dose? Get tested.
-
What helps diarrhea on a GLP-1?
Fluids with electrolytes first, plain food, a check of your magnesium and sweeteners, then OTC options. Call if it lasts 2+ days, or with blood or fever.
-
Should I skip my GLP-1 shot if I’m constipated?
Not on your own. Treat ordinary constipation and call your prescriber before skipping. Pain, vomiting or no gas with constipation needs a same-day call.
-
Is it normal to have no appetite at all on a GLP-1?
Low appetite is how a GLP-1 works, and some people feel none at all. Normal, but you still need fluids, protein and a floor of food every day.
-
Should I stay on a lower dose of a GLP-1 if it’s working?
Often yes, if it is a labeled maintenance dose: Zepbound 5 mg and Wegovy 1.7 mg count. Starter doses do not. The call is your prescriber’s.